BIOSS

Centre for Biological Signalling Studies

News

Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters

March 22, 2024 No Comments

2 new DFG research units at the University of Freiburg

The research unit “UcarE – Urothelial Carcinoma Epigenetics” aims to investigate the biological mechanisms that underlie bladder cancer. The unit’s spokesman is Prof Dr Ian

September 22, 2023 No Comments

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Glowing molecules and the memories of plants:

July 28, 2023 No Comments

Events

Heiko Heerklotz

BIOSS and Institute of Pharmaceutical Sciences, University of Freiburg
Professor for Pharmaceutics and Bioss Core Professor

+49 761 203 6338

heiko.heerklotz@pharmazie.uni-freiburg.de

https://www.pharmtech.uni-freiburg.de/mitarbeiterinnen/heiko-heerklotz

Curriculum vitae

10 selected publications

Complex electrostatic effects on the selectivity of membrane-permeabilizing cyclic lipopeptides. Steigenberger J, Verleysen Y, Geudens N, Madder A, Martins JC, Heerklotz H (2023). Biophys J. 122(6):950-963.
Complex Micellization Behavior of the Polysorbates Tween 20 and Tween 80. Knoch H, Ulbrich MH, Mittag JJ, Buske J, Garidel P, Heerklotz H (2021). Mol Pharm. 18(8):3147-3157.
Stairway to Asymmetry: Five Steps to Lipid-Asymmetric Proteoliposomes. Markones M, Fippel A, Kaiser M, Drechsler C, Hunte C, Heerklotz H (2020). Biophys J. 118(2):294-302.
Characterizing vesicle leakage by fluorescence lifetime measurements. Patel H, Tscheka C, Heerklotz H (2009). Soft Matter 5:2849-2851
Monitoring detergent-mediated solubilization and reconstitution of lipid membranes by isothermal titration calorimetry. Heerklotz H, Tsamaloukas A, Keller S (2009). Nat Protocols 4:686-697
Interactions of surfactants with lipid membranes. Heerklotz H (2008). Quarterly Reviews of Biophysics 41:205-264
Uptake and release protocol for assessing membrane binding and permeation by way of isothermal titration calorimetry. Tsamaloukas A, Keller S, Heerklotz H (2007). Nat Protocols 2:695-704
A quantitative model describing the selective solubilization of membrane domains. Keller S, Tsamaloukas , Heerklotz H (2005). J Am Chem Soc. 127:11469-11476
Structural, volumetric and thermodynamic characterization of a micellar sphere-to-rod transition. Heerklotz H, Tsamaloukas A, Kita-Tokarczyk K, Strunz P, Gutberlet T (2004). J Am Chem Soc. 126:16544
Triton promotes domain formation in ´lipid raft´ mixtures. Heerklotz H (2002). Biophys. J. 83:2693-2701