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The Minguet Group
Our work is centered in understanding the molecular mechanisms leading to the activation of B and T lymphocytes. The main focus of our group is to find out how lymphocytes transmit the information of ligand binding to their antigen receptors across the plasma membrane and which signaling mechanisms regulate activation. In addition, we are interested in the translational and synthetic applications of this knowledge, with special focus in T-cell immunotherapies against cancer.