BIOSS-A
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Membranes and protein–lipid interactions in signalling
BIOSS-B
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Oncogenic signalling
BIOSS-C
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Re-building & biotechnology
BIOSS
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From Analysis
to Synthesis
Prof. Dr. Carola Hunte
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Prof. Dr. Carola Hunte
BIOSS and Institute for Biochemistry and Molecular Biology, University of Freiburg
hired as BIOSS Professor
+49 761 203 5279
10 selected publications:
- Structural basis for safe and efficient energy conversion in a respiratory supercomplex.
Kao W-C*, Ortmann de Percin Northumberland C, Cheng TC, Julio Ortiz J, Durand A, von Loeffelholz O, Schilling O, Biniossek ML, Klaholz BP, Hunte C* (2022).
Nat Comm 13, 545 *corresponding - Mechanistic insight from the crystal structure of mitochondrial complex.
Zickermann V*, Wirth C, Nasiri H, Siegmund K, Schwalbe H, Hunte C*, Brandt U* (2015).
Science 347,44-49.
*corresponding - Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action.
Birth D, Kao WC, Hunte C (2014).
Nat Comm. 5, 4029. - Functional modules and structural basis of conformational coupling in mitochondrial complex I.
Hunte C*, Zickermann V*, Brandt U (2010).
Science 329, 448-451.
*equal contribution - Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer.
Solmaz SR, Hunte C (2008).
J Biol Chem. 283, 17542-17549. - Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH.
Hunte C*, Screpanti E, Venturi M, Rimon A, Padan E*, Michel H* (2005).
Nature 435, 1197-1202.
*corresponding - Lipids in membrane protein structures.
Palsdottir H, Hunte C (2004).
Biochim Biophys Acta 1666, 2-18. - Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c.
Lange C, Hunte C (2002).
Proc Natl Acad Sci U S A 99, 2800-2805. - Specific roles of tightly bound phospholipids in the yeast cytochrome bc1 complex structure.
Lange C, Nett JH, Trumpower BL, Hunte C (2001).
EMBO J. 20, 6591-6600. - Structure at 2.3 Å resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.
Hunte C, Köpke J, Lange C, Roßmanith T, Michel H (2000).
Structure 8, 669-684.