Prof. Dr. Gerd Walz

10 selected publications:

• CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling.
  Zhang Z, Zhang F, Davis AK, Xin M, Walz G, Tian W, Zheng Y.
  Cell Rep. 2022 Jan 11;38(2):110009.
• Microridge-like structures anchor motile cilia.
  Yasunaga T, Wiegel J, Bergen MD, Helmstädter M, Epting D, Paolini A, Çiçek Ö, Radziwill G, Engel C, Brox T, Ronneberger O, Walentek P, Ulbrich MH, Walz G.
  Nat Commun. 2022 Apr 19;13(1):2056.
• Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans.
  Schlosser P, Li Y, Sekula P, Raffler J, Grundner-Culemann F, Pietzner M, Cheng Y, Wuttke M, Steinbrenner I, Schultheiss UT, Kotsis F, Kacprowski T, Forer L, Hausknecht B, Ekici AB, Nauck M, Völker U; GCKD Investigators; Walz G, Oefner PJ, Kronenberg F, Mohney RP, Köttgen M, Suhre K, Eckardt KU, Kastenmüller G, Köttgen A.
  Nat Genet. 2020 Feb;52(2):167-176
• A molecular mechanism explaining albuminuria in kidney disease.
  Butt L, Unnersjö-Jess D, Höhne M, Edwards A, Binz-Lotter J, Reilly D, Hahnfeldt R, Ziegler V, Fremter K, Rinschen MM, Helmstädter M, Ebert LK, Castrop H, Hackl MJ, Walz G, Brinkkoetter PT, Liebau MC, Tory K, Hoyer PF, Beck BB, Brismar H, Blom H, Schermer B, Benzing T.
  Nat Metab. 2020 May;2(5):461-474.
• Primary decidual zone formation requires Scribble for pregnancy success in mice.
  Yuan J, Aikawa S, Deng W, Bartos A, Walz G, Grahammer F, Huber TB, Sun X, Dey SK.
  Nat Commun. 2019 Nov 28;10(1):5425.
• CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury.
  Yakulov TA, Todkar AP, Slanchev K, Wiegel J, Bona A, Gross M, Scholz A, Hess I, Wurditsch A, Grahammer F, Huber TB, Lecaudey V, Bork T, Hochrein J, Boerries M, Leenders J, de Tullio P, Jouret F, Kramer-Zucker A, and Walz G (2018).
  Nat Commun 9, 3660.
• Autosomal dominant polycystic kidney disease: the changing face of clinical management.
  Ong AC, Devuyst O, Knebelmann B, Walz G (2015).
  Lancet 385, 1993-2002.
• ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
  Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstadter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS (2013).
  Nat Genet 45, 951-956.
• Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension.
  Lienkamp SS, Liu K, Karner CM, Carroll TJ, Ronneberger O, Wallingford JB, Walz G (2012).
  Nat Genet 44, 1382-1387.
• Everolimus in patients with autosomal dominant polycystic kidney disease.
  Walz G, Budde K, Mannaa M, Nurnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Horl WH, Obermuller N, Arns W, Pavenstadt H, Gaedeke J, Buchert M, May C, Gschaidmeier H, Kramer S, and Eckardt KU.
  N Engl J Med 363, 830-840 (2010).