BIOSS
Centre for Biological Signalling Studies

Prof. Dr. Khaled Selim

Prof. Dr. Khaled Selim

Faculty of Biology, Microbiology, Freiburg University

+49 761 203 2638

10 selected publications

  • Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA.
    Selim KA*, Haffner M, Mantovani O, Albrecht R, Zhu H, Hagemann M, Forchhammer K, Hartmann MD*. (2023)
    Proc Natl Acad Sci USA 120(8):e2205882120.
  • New views on PII signaling: from nitrogen sensing to global metabolic control.
    Forchhammer K*, Selim KA*, Huergo LF* (2022)
    Trends Microbiol, 30(8):722-735.
  • Native metabolomics identifies the rivulariapeptolide family of protease inhibitors in cyanobacteria.
    Reher R, Aron AT, Fajtová P, Stincone P, Wagner B, Pérez-Lorente AI, Liu C, Shalom IYB, Bittremieux W, Wang M, Jeong K, Matos-Hernandez ML, Alexander KL, Caro-Diaz EJ, Naman CB, Scanlan JHW, Hochban PMM, Diederich WE, Molina-Santiago C, Romero D, Selim KA, Sass P, Brötz-Oesterhelt H, Hughes CC, Dorrestein PC, O'Donoghue AJ, Gerwick WH, Petras D. (2022)
    Nature Communication, 13, 4619.
  • The impact of the cyanobacterial carbon-regulator protein SbtB and of the second messengers cAMP and c-di-AMP on CO2-dependent gene expression.
    Oliver M, Reimann V, Haffner M, Herrmann F, Selim KA, Forchhammer K, Hess W, Hagemann M. (2022)
    New Phytologist, 234(5):1801-1816.
  • Diurnal metabolic control in cyanobacteria requires perception of second messenger signaling molecule c-di-AMP by the carbon-control protein SbtB.
    Selim KA#*, Haffner M#, Burkhardt M, Mantovani O, Neumann N, Albrecht R, Seifert R, Krüger L, Stülke J, Hartmann MD, Hagemann M, Forchhammer K*. (2021)
    Science Advances, 7(50): eabk0568. 6.
  • Functional and structural characterization of PII-like protein CutA does not support involvement in heavy metal tolerance in cyanobacteria and hints at a small-molecule carrying/signaling role.
    Selim KA#*, Tremiño L#, Marco-Marín C, Alva V, Espinosa J, Contreras A, Hartmann MD, Forchhammer K, Rubio V*. (2021)
    FEBS J, 288(4):1142-1162. 7.
  • Interaction of N-acetyl-l-glutamate kinase with the PII signal transducer in the non-photosynthetic alga Polytomella parva: Co-evolution towards a hetero-oligomeric enzyme.
    Selim KA, Lapina T, Forchhammer K, Ermilova E. (2020)
    FEBS J, 287(3):465-482.
  • Tuning the in vitro sensing and signaling properties of cyanobacterial PII protein by mutation of key residues.
    Selim KA*, Haffner M, Watzer B, Forchhammer K. (2019)
    Scientific Reports, 9(1):18985
  • A novel Ca2+-binding protein influences photosynthetic electron transport in Anabaena sp.
    Walter J, Selim KA, Leganés F, Fernández-Piñas F, Vothknecht UC, Forchhammer K, Aro EM, Gollan PJ. (2019)
    Biochim Biophys Acta Bioenerg, 1860(6):519-532.
  • PII-like signaling protein SbtB links cAMP sensing with cyanobacterial inorganic carbon response.
    Selim KA*, Haase F, Hartmann MD, Hagemann M, Forchhammer K*. (2018)
    Proc Natl Acad Sci USA, 115(21): E4861.