Prof. Dr. Nikolaus Pfanner

10 selected publications:

• Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth.
  Rampelt H, Wollweber F, Licheva M, de Boer R, Perschil I, Steidle L, Becker T, Bohnert M, van der Klei I, Kraft C, van der Laan M, Pfanner N (2022)
  Cell Rep. 38, 110290.
• Mitochondrial proteins: from biogenesis to functional networks.
  Pfanner N, Warscheid B, Wiedemann, N (2019)
  Nat Rev Mol Cell Biol 20, 267-284.
• Structure of the mitochondrial import gate reveals distinct preprotein paths.
  Araiso Y, Tsutsumi A, Qiu J, Imai K, Shiota T, Song J, Lindau C, Wenz LS, Sakaue H, Yunoki K, Kawano S, Suzuki J, Wischnewski M, Schütze C, Ariyama H, Ando T, Becker T, Lithgow T, Wiedemann N, Pfanner N, Kikkawa M, Endo T (2019)
  Nature 575, 395-401.
• Dual role of mitochondrial porin in metabolite transport across the outer membrane and protein transfer to the inner membrane.
  Ellenrieder L, Dieterle MP, Doan KN, Martensson CU, Floerchinger A, Campo ML, Pfanner N*,#, Becker, T* (2019)
  *corresponding #lead contact
• Membrane protein insertion through a mitochondrial β-barrel gate.
  Höhr AIC, Lindau C, Wirth C, Qiu J, Stroud DA, Kutik S, Guiard B, Hunte C, Becker T, Pfanner N*, Wiedemann N* (2018).
  Science 359, eaah6834   *corresponding
• Mitochondrial OXA translocase plays a major role in biogenesis of inner-membrane proteins.
  Stiller SB, Höpker J, Oeljeklaus S, Schütze C, Schrempp SG, Vent-Schmidt J, Horvath SE, Frazier AE, Gebert N, van der Laan M, Bohnert M, Warscheid B, Pfanner N*, Wiedemann, N* (2016).
  Cell Metab. 23, 901-8.
  *corresponding
• Central role of Mic10 in the mitochondrial contact site and cristae organizing system.
  Bohnert M, Zerbes RM, Davies KM, Mühleip AW, Rampelt H, Horvath SE, Boenke T, Kram A, Perschil I, Veenhuis M, Kühlbrandt W, van der Klei IJ, Pfanner N*, van der Laan M* (2015).
  Cell Metab. 21, 747-55.
  *corresponding
• Cell cycle-dependent regulation of mitochondrial preprotein translocase.
  Harbauer AB, Opalińska M, Gerbeth C, Herman JS, Rao S, Schönfisch B, Guiard B, Schmidt O, Pfanner N*, Meisinger C* (2014).
  Science 346, 1109-13.
  *corresponding
• Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane.
  Ieva R, Schrempp SG, Opaliński L, Wollweber F, Höß P, Heißwolf AK, Gebert M, Zhang Y, Guiard B, Rospert S, Becker T, Chacinska A, Pfanner N*, van der Laan M* (2014).
  Mol Cell 56, 641-52.
  *corresponding
• Regulation of mitochondrial protein import by cytosolic kinases.
  Schmidt O, Harbauer AB, Rao S, Eyrich B, Zahedi RP, Stojanovski D, Schönfisch B, Guiard B, Sickmann A, Pfanner N*, Meisinger C* (2011).
  Cell 144, 227-39.
  *corresponding