CNK1 and other scaffolds for Akt/FoxO signaling.

12.02.2011

Fritz RD, Radziwill G.

Biochim Biophys Acta. 2011;1813(11):1971-7

Biochim Biophys Acta.        online article

This review is part of a special issue on “PI3K-Akt-FoxO axis in cancer and aging”. In our article we summarize and discuss the latest findings on scaffold proteins as regulators of signaling pathways. Special interest is placed on CNK´s function in regulation of FoxO proteins in cancer and cell fate decision.