The mitochondrial protein import machinery has multiple connections to the respiratory chain

26.12.2012

Kulawiak B, Höpker J, Gebert M, Guiard B, Wiedemann N, Gebert N.

Biochim Biophys Acta. 2013 May;1827(5):612-26

The mitochondrial inner membrane harbors the complexes of the respiratory chain and protein translocases required for the import of mitochondrial precursor proteins. These complexes are functionally interdependent. Besides this basic codependency four different systems for protein import, processing and assembly show further connections to the respiratory chain. In this review we will summarize the import of mitochondrial precursor proteins and highlight these special links between the mitochondrial protein import machinery and the respiratory chain.

BIOSS

The mitochondrial protein import machinery has multiple connections to the respiratory chain