Microglia fuel the learning brain

11.03.2014

Blank T, Goldmann T, Prinz M

Trends Immunol. 2014 Apr;35(4):139-40

Trends Immunol.         online article

Microglia, the brain resident macrophages, are first responders to any violation of central nervous system (CNS) homeostasis. New data show that the specific depletion of microglia causes deficits in learning-induced synaptic remodeling through paucity of the microglial neurotrophin brain-derived neurotrophic factor (BDNF).