The LabTube - a novel microfluidic platform for assay automation in laboratory centrifuges
04.03.2014
Kloke A, Fiebach AR, Zhang S, Drechsel L, Niekrawietz S, Hoehl MM, Kneusel R, Panthel K, Steigert J, von Stetten F, Zengerle R, Paust N.
Lab Chip. 2014;14(9):1527-37
Assay automation is the key for successful transformation of modern biotechnology into routine workflows. Yet, it requires considerable investment in processing devices and auxiliary infrastructure, which is not cost-efficient for laboratories with low or medium sample throughput or point-of-care testing. To close this gap, we present the LabTube platform, which is based on assay specific disposable cartridges for processing in laboratory centrifuges. LabTube cartridges comprise interfaces for sample loading and downstream applications and fluidic unit operations for release of prestored reagents, mixing, and solid phase extraction.
