The potential of Physcomitrella patens as a platform for the production of plant-based vaccines
03.01.2014
Rosales-Mendoza S, Orellana-Escobedo L, Romero-Maldonado A, Decker EL, Reski R
Expert Rev Vaccines. 2014;13(2):203-12
Expert Rev Vaccines. online article
The moss Physcomitrella patens has a number of advantages for the production of biopharmaceuticals. In this opinion paper the possibilities of using P. patens for the production of oral vaccines is analyzed and some specific cases where its use may represent significant progress in the field of plant-based vaccine development are presented. The advantages represented by putative adjuvant effects of endogenous secondary metabolites and producing specific glycosylation patterns are highlighted.