News

Einblick in die Biologische Signalforschung in Freiburg

Der Oberbürgermeister von Freiburg, Martin Horn, besuchte kürzlich das Signalhaus Freiburg, ein Laborgebäude der Exzellenzcluster BIOSS (Biological Signalling Studies) und CIBSS (Centre for Integrative Biological Signalling Studies), um sich einen Überblick über die langjährige Tradition der...

Zwei neue DFG-Forschungsgruppen an der Universität Freiburg

Gruppen wollen neue Potenziale der enzymatischen Katalyse eröffnen sowie die biologischen Mechanismen erforschen, die Blasenkrebs zugrunde liegen

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Reversible biomechano-responsive surface based on green fluorescent protein genetically modified with unnatural amino acids

04.01.2015

Longo J, Yao C, Rios C, Chau NT, Boulmedais F, Hemmerlé J, Lavalle P, Schiller SM, Schaaf P, Jierry L.

Chem Commun (Camb). 2015;51(1):232-5

Chem Commun (Camb). online article

GFP has been genetically modified at two specific positions of its molecular architecture. These modifications allow its covalent attachment onto PEG brushes grafted on functionalized silicone surfaces. The stretching of this material leads to a reversible decrease of the fluorescence intensity due to stretch-induced forces applying on GFP molecules.