BIOSS
Centre for Biological Signalling Studies

Rigorous buoyancy driven bubble mixing for centrifugal microfluidics

25.11.2015

Burger S, Schulz M, von Stetten F, Zengerle R, Paust N.

Lab Chip. 2016;16(2):261-8.

Lab Chip           online article

We present batch-mode mixing for centrifugal microfluidics operated at fixed rotational frequency. Buoyancy driven bubble mixing is quantitatively compared to shake mode mixing, mixing by eciprocation and vortex mixing. We consider buoyancy driven bubble mixing an excellent alternative to shake mode mixing, in particular if the processing device is not capable of providing fast changes of rotational frequency or if the low average rotational frequency is challenging for the other integrated fluidic operations.