LabDisk for SAXS: a centrifugal microfluidic sample preparation platform for small-angle X-ray scattering
Schwemmer F, Blanchet CE, Spilotros A, Kosse D, Zehnle S, Mertens HD, Graewert MA, Rössle M, Paust N, Svergun DI, von Stetten F, Zengerle R, Mark D.
Lab Chip. 2016;16(7):1161-70.
We present a centrifugal microfluidic LabDisk for protein structure analysis via small-angle X-ray scattering (SAXS) on synchrotron beamlines. One LabDisk prepares 120 different measurement conditions, grouped into six dilution matrices. Total hands on time is less than 5 min and experiments can be performed by a non-expert.