BIOSS
Centre for Biological Signalling Studies

Role of the mitochondrial contact site and cristae organizing system in membrane architecture and dynamics

Rampelt H, Zerbes RM, van der Laan M, Pfanner N.

Biochim Biophys Acta. 2017 Apr;1864(4):737-746.

Biochim Biophys Acta.       online article

This review discusses the function and composition of the mitochondrial contact site and cristae organizing system (MICOS). MICOS is crucial for the architecture of mitochondria in healthy and defective cells.