Metabolic profiling of isolated mitochondria and cytoplasm reveals compartment-specific metabolic responses
Pan D, Lindau C, Lagies S, Wiedemann N, Kammerer B.
Metabolomics. 2018;14(5):59.
By applying metabolomics to isolated mitochondria and the corresponding cytoplasm, compartment-specific metabolic signatures can be identified. This subcellular metabolomics analysis is a powerful tool to study the molecular mechanism of compartment-specific metabolic homeostasis in response to mutations affecting the mitochondrial metabolism.
