Lab News

Marina Zintchenko, Trang Nguyen, Wolfgang Schamel and Susana Minguet write a review with colleagues together on “The potential of γδ CAR

 We enjoyed attending the 7th Upper Rhine Immunology (URI) Meeting in Basel, where early-career researchers from Basel, Karlsruhe, Freiburg, and

Trang Nguyen and Wolfgang Schamel are part of the study “Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity”.

TCR Signalling Technologies

In the past decade our group has constantly developed new methodologies and reagents to study signaling in T and B cells. Some of these reagents are of interest to other research groups or companies. To serve the demand, we have started a small university company called TCR Signalling Technologies, where several of the reagents can be purchased. All reagents are thoroughly tested in our group before shipment.

Currently, our portfolio includes:

Cell lines (mycoplasma-free):

ZL011: 31-13.scTCRVb3

ZL011: Jurkat.scTCRVb3

ZL012: Jurkat.TCRVb3GFP

ZL021: MA5.8.mzSBP

ZL022: MA5.8.mzGFPSBP

ZL031: 2B4.shKidins

ZL031: 2B4.shScrambled

Antibodies:

PA011: anti-phospho-CD3eY

PA012: anti-phospho-CD3z   

PA021: anti-CD3z

Beads:

BE001: nitro-phenol-coupled sepharose beads

Please contact Kerstin Fehrenbach (Email: kerstin.fehrenbach(at)biologie.uni-freiburg.de) in case of interest.