BIOSS-A
Membranes and protein–lipid interactions in signalling
BIOSS-B
Oncogenic signalling
BIOSS-C
Re-building & biotechnology
BIOSS
From Analysis
to Synthesis
Publications
- Spatially Defined Gene Delivery into Native Cells with the Red Light-Controlled OptoAAV Technology.
Hörner M, Weber W.
Curr Protoc. 2022 Jun;2(6):e440. - Benchmarking of Cph1 Mutants and DrBphP for Light-Responsive Phytochrome-Based Hydrogels with Reversibly Adjustable Mechanical Properties.
Emig R, Hoess P, Cai H, Kohl P, Peyronnet R, Weber W, Hörner M.
Adv Biol (Weinh). 2022 Apr 28:e2000337. Online ahead of print. - Reversible Shielding and Immobilization of Liposomes and Viral Vectors by Tailored Antibody‐Ligand Interactions
Thomas OS, Rebmann B, Tonn M, Schirmeister IC, Wehrle S, Becker J, Zea Jimenez GJ, Hook S, Jäger S, Klenzendorf M, Laskowski M, Kaier A, Pütz G, Zurbriggen MD, Weber W, Hörner M, Wagner HJ
Small. 2021 Dec 3:e2105157 - Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors.
Hörner M, Jerez-Longres C, Hudek A, Hook S, Yousefi OS, Schamel WWA, Hörner C, Zurbriggen MD, Ye H, Wagner HJ, Weber W.
Sci Adv. 2021 Jun 16;7(25):eabf0797. - Synthetic biology as driver for the biologization of materials sciences.
Burgos-Morales O, Gueye M, Lacombe L, Nowak C, Schmachtenberg R, Hörner M, Jerez-Longres C, Mohsenin H, Wagner HJ, Weber W.
Mater Today Bio. 2021 May 26;11:100115. - Liquid-liquid phase separation of light-inducible transcription factors
Schneider N, Wieland FG, Kong D, Fischer AAM, Hörner M, Timmer J, Ye H, Weber W.
Sci Adv. 2020 Jan 1;7(1): eabd3568. - A graphical user interface to design high-throughput optogenetic experiments with the optoPlate-96.
Thomas OS, Hörner M, Weber W.
Nat Protoc. 2020 Sep;15(9):2785-2787. - Synthesis of a Light-Controlled Phytochrome-Based Extracellular Matrix with Reversibly Adjustable Mechanical Properties.
Hörner M, Hoess P, Emig R, Rebmann B, Weber W.
Methods Mol Biol. 2020;2173:217-231. - Production, Purification and Characterization of Recombinant Biotinylated Phytochrome B for Extracellular Optogenetics
Hörner M, Yousefi OS, Schamel WWA, Weber W.
Bio Protoc. 2020 Mar 05;10(5):e3541. - Optogenetic Tuning of Ligand Binding to The Human T cell Receptor Using The opto-ligand-TCR System
Yousefi OS, Hörner M, Wess M, Idstein V, Weber W, Schamel WWA.
Bio Protoc. 2020 Mar 05;10(5):e3540. - Human Atrial Fibroblast Adaptation to Heterogeneities in Substrate Stiffness.
Emig R, Zgierski-Johnston CM, Beyersdorf F, Rylski B, Ravens U, Weber W, Kohl P, Hörner M, Peyronnet R.
Front Physiol. 2020 Jan 10;10:1526. - Production of Phytochromes by High-Cell-Density E. coli Fermentation.
Hörner M, Gerhardt K, Salavei P, Hoess P, Härrer D, Kaiser J, Tabor JJ, Weber W.
ACS Synth Biol. 2019 Oct 18;8(10):2442-2450. - Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor.
Yousefi OS, Günther M, Hörner M, Chalupsky J, Wess M, Brandl SM, Smith RW, Fleck C, Kunkel T, Zurbriggen MD, Höfer T, Weber W, Schamel WW.
Elife. 2019 Apr 5;8. pii: e42475. - Light-Controlled Affinity Purification of Protein Complexes Exemplified by the Resting ZAP70 Interactome.
Hörner M, Eble J, Yousefi OS, Schwarz J, Warscheid B, Weber W, Schamel WWA.
Front Immunol. 2019 Feb 26;10:226. - Optogenetic control of integrin–matrix interaction.
Baaske J, Mühlhäuser WWD, Yousefi OS, Zanner S, Radziwill G, Hörner M, Schamel WWA, Weber W (2019).
Commun Biol. 2019 Jan 8;2:15 - Phytochrome-based extracellular matrix with reversibly tunable mechanical properties
Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W
Adv Mater. 2019 Mar;31(12):e1806727. - Generic and reversible opto-trapping of biomolecules.
Beyer HM, Thomas OS, Riegel N, Zurbriggen MD, Weber W, Hörner M.
Acta Biomater. 2018 Oct 1;79:276-282. - Synthetic Biology makes polymer materials count
Beyer HM, Engesser R, Hörner M, Koschmieder J, Beyer P, Timmer J, Zurbriggen MD, Weber W.
Adv Mater. 2018 May;30(21):e1800472. - Optogenetic control of focal adhesion kinase signaling.
Hörner M, Chatelle C, Mühlhäuser WWD, Stocker DR, Coats M, Weber W, Radziwill G.
Cell Signal. 2018 Jan;42:176-183. - Light-responsive promoters.
Hörner M, Müller K, Weber W.
Methods Mol Biol. 2017;1651:173-186. - Light-regulated protein kinases based on the CRY2-CIB1 system.
Mühlhäuser WW, Hörner M, Weber W, Radziwill G.
Methods Mol Biol. 2017;1596:257-270. - Unearthing the transition rates between photoreceptor conformers.
Smith RW, Helwig B, Westphal AH, Pel E, Hörner M, Beyer HM, Samodelov SL, Weber W, Zurbriggen MD, Borst JW, Fleck C.
BMC Syst Biol. 2016 Nov 25;10(1):110. - A chemical switch for controlling viral infectivity.
Hörner M, Kaufmann B, Cotugno G, Wiedtke E, Büning H, Grimm D, Weber W.
Chem Commun (Camb). 2014 Sep 14;50(71):10319-22. - Comparative functional analysis of full-length and N-terminal fragments of phytochrome C, D and E in red light-induced signaling.
Ádám É, Kircher S, Liu P, Mérai Z, González-Schain N, Hörner M, Viczián A, Monte E, Sharrock RA, Schäfer E, Nagy F.
New Phytol. 2013 Oct;200(1):86-96. - Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis.
Beaudouin J, Liesche C, Aschenbrenner S, Hörner M, Eils R.
Cell Death Differ. 2013 Apr;20(4):599-610. - Molecular switches in animal cells.
Hörner M, Weber W.
FEBS Lett. 2012 Jul 16;586(15):2084-96. - Rewiring and dosing of systems modules as a design approach for synthetic mammalian signaling networks.
Kämpf MM, Engesser R, Busacker M, Hörner M, Karlsson M, Zurbriggen MD, Fussenegger M, Timmer J, Weber W.
Mol Biosyst. 2012 Jun;8(6):1824-32. - Synthetic biology: programming cells for biomedical applications.
Hörner M, Reischmann N, Weber W.
Perspect Biol Med. 2012;55(4):490-502. - Structural insights into cis element recognition of non-polyadenylated RNAs by the Nab3-RRM.
Lunde BM, Hörner M, Meinhart A.
Nucleic Acids Res. 2011 Jan;39(1):337-46.