BIOSS
Centre for Biological Signalling Studies

BIOSS-A

Membranes and protein–lipid interactions in signalling

BIOSS-B

Oncogenic signalling

BIOSS-C

Re-building & biotechnology

BIOSS

From Analysis
to Synthesis

Publications

  • A new branched proximity hybridization assay for the quantification of nanoscale protein-protein proximity.
    Zheng S, Sieder M, Mitterer M, Reth M, Cavallari M, Yang J (2019).
    PLoS Biol. 17(12):e3000569.
  • TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections.
    Savage HP, Kläsener K, Smith FL, Luo Z, Reth M, Baumgarth N (2019).
    Elife. 2019 Aug 21;8. pii: e46997.
  • A symmetric geometry of transmembrane domains inside the B cell antigen receptor complex.
    Gottwick C, He X, Hofmann A, Vesper N, Reth M, Yang J (2019).
    Proc Natl Acad Sci U S A. 116(27):13468-13473.
  • Antigen Receptor Function in the Context of the Nanoscale Organization of the B Cell Membrane.
    Gold MR, Reth MG (2019.
    Annu Rev Immunol. 37:97-123.
  • Pten controls B-cell responsiveness and germinal center reaction by regulating the expression of IgD BCR.
    Setz CS, Khadour A, Renna V, Iype J, Gentner E, He X, Datta M, Young M, Nitschke L, Wienands J, Maity PC, Reth M, Jumaa H (2019).
    EMBO J. 38(11). pii: e100249.
  • LAMTOR2 (p14) controls B cell differentiation by orchestrating endosomal BCR trafficking.
    Łyszkiewicz M, Kotlarz D, Ziȩtara N, Brandes G, Diestelhorst J, Glage S, Hobeika E, Reth M, Huber LA, Krueger A, Klein C.
    Front Immunol. 2019 Mar 18;10:497.
  • Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins.
    Wilhelm I, Levit-Zerdoun E, Jakob J, Villringer S, Frensch M, Übelhart R, Landi A, Müller P, Imberty A, Thuenauer R, Claudinon J, Jumaa H, Reth M, Eibel H, Hobeika E, Römer W.
    Sci Signal. 2019 Mar 5;12(571).
  • Synthetic biology of B cell activation: understanding signal amplification at the B cell antigen receptor using a rebuilding approach.
    Kulathu Y, Zuern C, Yang J, Reth M.
    Biol Chem. 2019 Mar 26;400(4):555-563.
  • Conditional Selection of B Cells in Mice With an Inducible B Cell Development.
    Hobeika E, Dautzenberg M, Levit-Zerdoun E, Pelanda R, Reth M.
    Front Immunol. 2018 Aug 6;9:1806.
  • First Infusion Reactions are Mediated by FcγRIIIb and Neutrophils.
    Weber F, Breustedt D, Schlicht S, Meyer CA, Niewoehner J, Ebeling M, Freskgard PO, Bruenker P, Singer T, Reth M, Iglesias A.
    Pharm Res. 2018 Jun 27;35(9):169
  • Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells.
    He X, Kläsener K, Iype JM, Becker M, Maity PC, Cavallari M, Nielsen PJ, Yang J, Reth M.
    EMBO J. 2018 Apr 18. [Epub ahead of print]
  • Foxp1 controls mature B cell survival and the development of follicular and B-1 B cells.
    Patzelt T, Keppler SJ, Gorka O, Thoene S, Wartewig T, Reth M, Förster I, Lang R, Buchner M, Ruland J.
    Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3120-3125.
  • Study B cell antigen receptor nano-scale organization by in situ Fab Proximity Ligation Assay.
    Kläsener K, Yang J, Reth M.
    Methods Mol Biol. 2018;1707:171-181.
  • Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.
    Minguet S, Kläsener K, Schaffer AM, Fiala GJ, Osteso-Ibánez T, Raute K, Navarro-Lérida I, Hartl FA, Seidl M, Reth M, Del Pozo MA.
    Nat Immunol. 2017 Oct;18(10):1150-1159.
  • The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex.
    Dolezal E, Infantino S, Drepper F, Börsig T, Singh A, Wossning T, Fiala GJ, Minguet S, Warscheid B, Tarlinton DM, Jumaa H, Medgyesi D, Reth M.
    Nat Immunol. 2017 Aug;18(8):911-920.
  • CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor.
    Becker M, Hobeika E, Jumaa H, Reth M, Maity PC.
    Proc Natl Acad Sci U S A. 2017 May 16;114(20):5231-5236.
  • The IgM receptor FcμR limits tonic BCR signaling by regulating expression of the IgM BCR.
    Nguyen TT, Kläsener K, Zürn C, Castillo PA, Brust-Mascher I, Imai DM, Bevins CL, Reardon C, Reth M, Baumgarth N.
    Nat Immunol. 2017 Mar;18(3):321-333.
  • LED Thermo Flow - Combining Optogenetics with Flow Cytometry.
    Brenker K, Osthof K, Yang J, Reth M.
    J Vis Exp. 2016 Dec 30;(118).
  • Spleen Tyrosine Kinase is involved in the CD38 signal transduction pathway in chronic lymphocytic leukemia.
    Benkisser-Petersen M, Buchner M, Dörffel A, Dühren-von-Minden M, Claus R, Kläsener K, Leberecht K, Burger M, Dierks C, Jumaa H, Malavasi F, Reth M, Veelken H, Duyster J, Zirlik K.
    PLoS One. 2016 Dec 30;11(12):e0169159.
  • What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling.
    Reth M, Gold MR.
    Eur J Immunol. 2016 Nov;46(11):2507-2511.
  • Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens.
    Volkmann C, Brings N, Becker M, Hobeika E, Yang J, Reth M.
    EMBO J. 2016 Nov 2;35(21):2371-2381.
  • Survival of Igα-deficient mature B cells requires BAFF-R function.
    Levit-Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity PC, Rajewsky K, Reth M, Hobeika E.
    J Immunol. 2016 Mar 1;196(5):2348-60.
  • Receptor dissociation and B-cell activation.
    Yang J, Reth M.
    Curr Top Microbiol Immunol. 2016;393:27-43.
  • B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation.
    Maity PC, Blount A, Jumaa H, Ronneberger O, Lillemeier BF, Reth M.
    Sci Signal. 2015 Sep 15;8(394):ra93.
  • Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.
    Fiala GJ, Janowska I, Prutek F, Hobeika E, Satapathy A, Sprenger A, Plum T, Seidl M, Dengjel J, Reth M, Cesca F, Brummer T, Minguet S, Schamel WW.
    J Exp Med. 2015 Sep 21;212(10):1693-708.
  • Processing of CD74 by the intramembrane protease SPPL2a is critical for B cell receptor signaling in transitional B cells.
    Hüttl S, Kläsener K, Schweizer M, Schneppenheim J, Oberg HH, Kabelitz D, Reth M, Saftig P, Schröder B.
    J Immunol. 2015 Aug 15;195(4):1548-63.
  • Responsiveness of B cells is regulated by the hinge region of IgD.
    Übelhart R, Hug E, Bach MP, Wossning T, Dühren-von Minden M, Horn AH, Tsiantoulas D, Kometani K, Kurosaki T, Binder CJ, Sticht H, Nitschke L, Reth M, Jumaa H.
    Nat Immunol. 2015 May;16(5):534-43.
  • Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
    Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M.
    Nature. 2015 May 21;521(7552):357-61
  • TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition.
    Thien A, Prentzell MT, Holzwarth B, Kläsener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K.
    Dev Cell. 2015 Mar 9;32(5):617-30.
  • Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.
    Busch K, Klapproth K, Barile M, Flossdorf M, Holland-Letz T, Schlenner SM, Reth M, Höfer T, Rodewald HR.
    Nature. 2015 Feb 26;518(7540):542-6.
  • Preface to special issue on nanoscale membrane organisations.
    Alarcón B, Reth M, Schamel W.
    Biochim Biophys Acta. 2015 Apr;1853(4):765-6.
  • CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
    Hobeika E, Levit-Zerdoun E, Anastasopoulou V, Pohlmeyer R, Altmeier S, Alsadeq A, Dobenecker MW, Pelanda R, Reth M.
    EMBO J. 2015 Apr 1;34(7):925-39.
  • The nanoscale organization of the B lymphocyte membrane.
    Maity PC, Yang J, Klaesener K, Reth M.
    Biochim Biophys Acta. 2015 Apr;1853(4):830-40.
  • Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms.
    Königsberger S, Weis V, Prodöhl J, Stehling M, Hobeika E, Reth M, Kiefer F.
    Eur J Immunol. 2015 Feb;45(2):603-11.
  • The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells.
    Grötsch B, Brachs S, Lang C, Luther J, Derer A, Schlötzer-Schrehardt U, Bozec A, Fillatreau S, Berberich I, Hobeika E, Reth M, Wagner EF, Schett G, Mielenz D, David JP.
    J Exp Med. 2014 Oct 20;211(11):2199-212.
  • Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE.
    Umiker BR, McDonald G, Larbi A, Medina CO, Hobeika E, Reth M, Imanishi-Kari T.
    Eur J Immunol. 2014 Oct;44(10):3093-108.
  • PDK1 regulates B cell differentiation and homeostasis.
    Baracho GV, Cato MH, Zhu Z, Jaren OR, Hobeika E, Reth M, Rickert RC.
    Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9573-8.
  • B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk.
    Kläsener K, Maity PC, Hobeika E, Yang J, Reth M.
    Elife. 2014 Jun 24;3:e02069.
  • The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling.
    Alsadeq A, Hobeika E, Medgyesi D, Kläsener K, Reth M.
    J Immunol. 2014 Jul 1;193(1):268-76.
  • The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells.
    Hutzler S, Özgör L, Naito-Matsui Y, Kläsener K, Winkler TH, Reth M, Nitschke L.
    J Immunol. 2014 Jun 1;192(11):5406-14.
  • MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling.
    Klasen C, Ohl K, Sternkopf M, Shachar I, Schmitz C, Heussen N, Hobeika E, Levit-Zerdoun E, Tenbrock K, Reth M, Bernhagen J, El Bounkari O.
    J Immunol. 2014 Jun 1;192(11):5273-84.
  • Pillars article: antigen receptor tail clue. Nature. 1989. 338: 383-384.
    Reth M.
    J Immunol. 2014 May 1;192(9):4015-6.
  • The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity.
    Medgyesi D, Hobeika E, Biesen R, Kollert F, Taddeo A, Voll RE, Hiepe F, Reth M.
    J Exp Med. 2014 Mar 10;211(3):427-40.
  • Signaling circuits in early B-cell development.
    Reth M, Nielsen P.
    Adv Immunol. 2014;122:129-75.
  • Michael Neuberger (1953-2013).
    Alt F, Reth M.
    Immunity. 2013 Dec 12;39(6):987-8.
  • Pre-clustering of the B cell antigen receptor demonstrated by mathematically extended electron microscopy.
    Fiala GJ, Kaschek D, Blumenthal B, Reth M, Timmer J, Schamel WW.
    Front Immunol. 2013 Dec 6;4:427.
  • Proximity ligation assay for high-content profiling of cell signaling pathways on a microfluidic chip.
    Blazek M, Betz C, Hall MN, Reth M, Zengerle R, Meier M.
    Mol Cell Proteomics. 2013 Dec;12(12):3898-907.
  • Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation.
    Hug E, Hobeika E, Reth M, Jumaa H.
    Oncogene. 2014 Jul 10;33(28):3730-41.
  • Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.
    Thedieck K, Holzwarth B, Prentzell MT, Boehlke C, Kläsener K, Ruf S, Sonntag AG, Maerz L, Grellscheid SN, Kremmer E, Nitschke R, Kuehn EW, Jonker JW, Groen AK, Reth M, Hall MN, Baumeister R.
    Cell. 2013 Aug 15;154(4):859-74.
  • The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination.
    Su YW, Chen YP, Chen MY, Reth M, Tan TH.
    PLoS One. 2013 Jul 16;8(7):e68804.
  • Matching cellular dimensions with molecular sizes.
    Reth M.
    Nat Immunol. 2013 Aug;14(8):765-7.
  • CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling.
    Müller J, Obermeier I, Wöhner M, Brandl C, Mrotzek S, Angermüller S, Maity PC, Reth M, Nitschke L.
    Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12402-7.
  • Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data.
    Kundu K, Costa F, Huber M, Reth M, Backofen R.
    PLoS One. 2013 May 17;8(5):e62732.
  • Immunoglobulins drive terminal maturation of splenic dendritic cells.
    Zietara N, Łyszkiewicz M, Puchałka J, Pei G, Gutierrez MG, Lienenklaus S, Hobeika E, Reth M, Martins dos Santos VA, Krueger A, Weiss S.
    Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2282-7.
  • Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors.
    Cooper CL, Hardy RR, Reth M, Desiderio S.
    Blood. 2012 Jun 7;119(23):5438-48.
  • Synthetic immune signaling.
    Schamel WW, Reth M.
    Curr Opin Biotechnol. 2012 Oct;23(5):780-4.
  • The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.
    Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, Detmar J, Jurisicova A, Hobeika E, Reth M, Sheng Y, Lang PA, Ohashi PS, Zhong Q, Wang X, Mak TW.
    J Exp Med. 2012 Jan 16;209(1):173-86.
  • The SH2-domain of SHIP1 interacts with the SHIP1 C-terminus: impact on SHIP1/Ig-α interaction.
    Mukherjee O, Weingarten L, Padberg I, Pracht C, Sinha R, Hochdörfer T, Kuppig S, Backofen R, Reth M, Huber M.
    Biochim Biophys Acta. 2012 Feb;1823(2):206-14.
  • Drosophila S2 Schneider cells: a useful tool for rebuilding and redesigning approaches in synthetic biology.
    Yang J, Reth M.
    Methods Mol Biol. 2012;813:331-41.
  • Bacillus subtilis MreB orthologs self-organize into filamentous structures underneath the cell membrane in a heterologous cell system.
    Dempwolff F, Reimold C, Reth M, Graumann PL.
    PLoS One. 2011;6(11):e27035.
  • B cells that produce immunoglobulin E mediate colitis in BALB/c mice.
    Hoving JC, Kirstein F, Nieuwenhuizen NE, Fick LC, Hobeika E, Reth M, Brombacher F.
    Gastroenterology. 2012 Jan;142(1):96-108.
  • Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations.
    Rowh MA, DeMicco A, Horowitz JE, Yin B, Yang-Iott KS, Fusello AM, Hobeika E, Reth M, Bassing CH.
    Oncogene. 2011 Nov 24;30(47):4757-64.
  • B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2.
    Winkelmann R, Sandrock L, Porstner M, Roth E, Mathews M, Hobeika E, Reth M, Kahn ML, Schuh W, Jäck HM.
    Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):710-5.
  • Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor.
    Heizmann B, Reth M, Infantino S.
    Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18563-8.
  • The dissociation activation model of B cell antigen receptor triggering.
    Yang J, Reth M.
    FEBS Lett. 2010 Dec 15;584(24):4872-7.
  • Oligomeric organization of the B-cell antigen receptor on resting cells.
    Yang J, Reth M.
    Nature. 2010 Sep 23;467(7314):465-9.
  • N-linked glycosylation selectively regulates autonomous precursor BCR function.
    Ubelhart R, Bach MP, Eschbach C, Wossning T, Reth M, Jumaa H.
    Nat Immunol. 2010 Aug;11(8):759-65.
  • Arginine methylation of the B cell antigen receptor promotes differentiation.
    Infantino S, Benz B, Waldmann T, Jung M, Schneider R, Reth M.
    J Exp Med. 2010 Apr 12;207(4):711-9.
  • Voltage control for B cell activation.
    Reth M, Dick TP.
    Nat Immunol. 2010 Mar;11(3):191-2.
  • Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling.
    Dopfer EP, Schöpf B, Louis-Dit-Sully C, Dengler E, Höhne K, Klescová A, Prouza M, Suchanek M, Reth M, Schamel WW.
    Immunol Lett. 2010 May 4;130(1-2):43-50.
  • Autoinhibition and adapter function of Syk.
    Kulathu Y, Grothe G, Reth M.
    Immunol Rev. 2009 Nov;232(1):286-99.
  • Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells.
    Düber S, Hafner M, Krey M, Lienenklaus S, Roy B, Hobeika E, Reth M, Buch T, Waisman A, Kretschmer K, Weiss S.
    Blood. 2009 Dec 3;114(24):4960-7.
  • Molecular components of the B-cell antigen receptor complex of the IgM class. 1990.
    Hombach J, Tsubata T, Leclercq L, Stappert H, Reth M.
    J Immunol. 2009 Aug 1;183(3):1505-7.
  • Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling.
    Herzog S, Reth M, Jumaa H.
    Nat Rev Immunol. 2009 Mar;9(3):195-205.
  • Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage.
    Babbe H, McMenamin J, Hobeika E, Wang J, Rodig SJ, Reth M, Leder P.
    J Immunol. 2009 Jan 1;182(1):347-60.
  • Clustering models.
    Schamel WW, Reth M.
    Adv Exp Med Biol. 2008;640:64-73.
  • Enhanced B-cell activation mediated by TLR4 and BCR crosstalk.
    Minguet S, Dopfer EP, Pollmer C, Freudenberg MA, Galanos C, Reth M, Huber M, Schamel WW.
    Eur J Immunol. 2008 Sep;38(9):2475-87.
  • Functional analysis of histone methyltransferase g9a in B and T lymphocytes.
    Thomas LR, Miyashita H, Cobb RM, Pierce S, Tachibana M, Hobeika E, Reth M, Shinkai Y, Oltz EM.
    J Immunol. 2008 Jul 1;181(1):485-93.
  • SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.
    Herzog S, Hug E, Meixlsperger S, Paik JH, DePinho RA, Reth M, Jumaa H.
    Nat Immunol. 2008 Jun;9(6):623-31.
  • The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.
    Kulathu Y, Hobeika E, Turchinovich G, Reth M.
    EMBO J. 2008 May 7;27(9):1333-44.
  • Riverine discharge of perfluorinated carboxylates from the European continent.
    McLachlan MS, Holmstrom KE, Reth M, Berger U.
    Environ Sci Technol. 2007 Nov 1;41(21):7260-5.
  • The TCR binding site does move.
    Schamel WW, Reth M.
    Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16398-9.
  • Mutations of the Igbeta gene cause agammaglobulinemia in man.
    Ferrari S, Lougaris V, Caraffi S, Zuntini R, Yang J, Soresina A, Meini A, Cazzola G, Rossi C, Reth M, Plebani A.
    J Exp Med. 2007 Sep 3;204(9):2047-51.
  • Immunoreceptors and integrins.
    Schraven B, Reth M.
    Immunol Rev. 2007 Aug;218:5-8.
  • Yin Yang 1 is a critical regulator of B-cell development.
    Liu H, Schmidt-Supprian M, Shi Y, Hobeika E, Barteneva N, Jumaa H, Pelanda R, Reth M, Skok J, Rajewsky K, Shi Y.
    Genes Dev. 2007 May 15;21(10):1179-89.
  • Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination.
    Totsugawa T, Yong C, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Westerman KA, Kohara M, Reth M, Tanaka N, Leboulch P, Kobayashi N.
    J Hepatol. 2007 Jul;47(1):74-82.
  • Association of protein kinase C-delta with the B cell antigen receptor complex.
    Pracht C, Minguet S, Leitges M, Reth M, Huber M.
    Cell Signal. 2007 Apr;19(4):715-22.
  • Testing gene function early in the B cell lineage in mb1-cre mice.
    Hobeika E, Thiemann S, Storch B, Jumaa H, Nielsen PJ, Pelanda R, Reth M.
    Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13789-94.
  • Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system.
    Siegers GM, Yang J, Duerr CU, Nielsen PJ, Reth M, Schamel WW.
    Int Immunol. 2006 Sep;18(9):1385-96.
  • Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation.
    Sasaki Y, Derudder E, Hobeika E, Pelanda R, Reth M, Rajewsky K, Schmidt-Supprian M.
    Immunity. 2006 Jun;24(6):729-39.
  • Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein.
    Brummer T, Martin P, Herzog S, Misawa Y, Daly RJ, Reth M.
    Oncogene. 2006 Oct 12;25(47):6262-76.
  • Human T-cell leukemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB.
    Okamoto K, Fujisawa J, Reth M, Yonehara S.
    Genes Cells. 2006 Feb;11(2):177-91.
  • Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes.
    Swamy M, Kulathu Y, Ernst S, Reth M, Schamel WW.
    Immunol Lett. 2006 Apr 15;104(1-2):131-7.
  • B cell signaling and tumorigenesis.
    Jumaa H, Hendriks RW, Reth M.
    Annu Rev Immunol. 2005;23:415-45.
  • A leucine zipper in the N terminus confers membrane association to SLP-65.
    Köhler F, Storch B, Kulathu Y, Herzog S, Kuppig S, Reth M, Jumaa H.
    Nat Immunol. 2005 Feb;6(2):204-10.
  • Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line.
    Kanayama N, Todo K, Reth M, Ohmori H.
    Biochem Biophys Res Commun. 2005 Feb 4;327(1):70-5.
  • Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors.
    Minguet S, Huber M, Rosenkranz L, Schamel WW, Reth M, Brummer T.
    Eur J Immunol. 2005 Jan;35(1):31-41.
  • Perspectives on the nature of BCR-mediated survival signals.
    Smith SH, Reth M.
    Mol Cell. 2004 Jun 18;14(6):696-7.
  • B-cell signal transduction: tyrosine phosphorylation, kinase activity, and calcium mobilization.
    Brummer T, Elis W, Reth M, Huber M.
    Methods Mol Biol. 2004;271:189-212.
  • Functional folding of a cytoplasmic single-chain variable fragment and its use as elutable protein purification tag.
    Elis W, Reth M, Huber M.
    Immunol Lett. 2004 Mar 29;92(1-2):185-92.
  • B cell antigen receptor assembly and Syk activation in the S2 cell reconstitution system.
    Wossning T, Reth M.
    Immunol Lett. 2004 Mar 29;92(1-2):67-73.
  • Feedback regulation of lymphocyte signalling.
    Reth M, Brummer T.
    Nat Rev Immunol. 2004 Apr;4(4):269-77.
  • 102. A revised and complete map of the chicken c-mil/raf-1 locus.
    Brummer T, Stéhelin D, Misawa Y, Reth M.
    Oncogene. 2004 Apr 15;23(17):3128-31.
  • Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells. Tsukiyama-Kohara K, Toné S, Maruyama I, Inoue K, Katsume A, Nuriya H, Ohmori H, Ohkawa J, Taira K, Hoshikawa Y, Shibasaki F, Reth M, Minatogawa Y, Kohara M.
    J Biol Chem. 2004 Apr 9;279(15):14531-41.
  • Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf.
    Brummer T, Naegele H, Reth M, Misawa Y.
    Oncogene. 2003 Dec 4;22(55):8823-34.
  • Identification of a pre-BCR lacking surrogate light chain.
    Su YW, Flemming A, Wossning T, Hobeika E, Reth M, Jumaa H.
    J Exp Med. 2003 Dec 1;198(11):1699-706.
  • B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling.
    Gerlach J, Ghosh S, Jumaa H, Reth M, Wienands J, Chan AC, Nitschke L.
    Eur J Immunol. 2003 Dec;33(12):3418-26.
  • Importance of TRF1 for functional telomere structure.
    Iwano T, Tachibana M, Reth M, Shinkai Y.
    J Biol Chem. 2004 Jan 9;279(2):1442-8.
  • A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum.
    Schamel WW, Kuppig S, Becker B, Gimborn K, Hauri HP, Reth M.
    Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9861-6.
  • Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.
    Kersseboom R, Middendorp S, Dingjan GM, Dahlenborg K, Reth M, Jumaa H, Hendriks RW.
    J Exp Med. 2003 Jul 7;198(1):91-8.
  • Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia.
    Jumaa H, Bossaller L, Portugal K, Storch B, Lotz M, Flemming A, Schrappe M, Postila V, Riikonen P, Pelkonen J, Niemeyer CM, Reth M.
    Nature. 2003 May 22;423(6938):452-6.
  • NF-kappaB is required for cell death induction by latent membrane protein 1 of Epstein-Barr virus.
    Nitta T, Chiba A, Yamashita A, Rowe M, Israël A, Reth M, Yamamoto N, Yamaoka S.
    Cell Signal. 2003 Apr;15(4):423-33.
  • Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development.
    Saijo K, Schmedt C, Su IH, Karasuyama H, Lowell CA, Reth M, Adachi T, Patke A, Santana A, Tarakhovsky A.
    Nat Immunol. 2003 Mar;4(3):274-9.
  • Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain.
    Losch FO, Müller R, Mutschler B, Neri D, Natali PG, Reth M, Carsetti R.
    Int J Cancer. 2003 Jan 20;103(3):399-407.
  • Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop.
    Rolli V, Gallwitz M, Wossning T, Flemming A, Schamel WW, Zürn C, Reth M.
    Mol Cell. 2002 Nov;10(5):1057-69.
  • Hydrogen peroxide as second messenger in lymphocyte activation.
    Reth M.
    Nat Immunol. 2002 Dec;3(12):1129-34.
  • The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.
    Flemming A, Brummer T, Reth M, Jumaa H.
    Nat Immunol. 2003 Jan;4(1):38-43.
  • Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling.
    Brummer T, Shaw PE, Reth M, Misawa Y.
    EMBO J. 2002 Nov 1;21(21):5611-22.
  • BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling.
    Pracht C, Gimborn K, Reth M, Huber M.
    Eur J Immunol. 2002 Jun;32(6):1614-20.
  • B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.
    Pelanda R, Braun U, Hobeika E, Nussenzweig MC, Reth M.
    J Immunol. 2002 Jul 15;169(2):865-72.
  • The role of SHIP in mast cell degranulation and IgE-induced mast cell survival.
    Huber M, Kalesnikoff J, Reth M, Krystal G.
    Immunol Lett. 2002 Jun 3;82(1-2):17-21.
  • The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.
    Breckenridge DG, Nguyen M, Kuppig S, Reth M, Shore GC.
    Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4331-6.
  • Cre recombinase-controlled expression of the mb-1 allele.
    Pelanda R, Hobeika E, Kurokawa T, Zhang Y, Kuppig S, Reth M.
    Genesis. 2002 Feb;32(2):154-7.
  • Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells.
    Fujimori A, Tachiiri S, Sonoda E, Thompson LH, Dhar PK, Hiraoka M, Takeda S, Zhang Y, Reth M, Takata M.
    EMBO J. 2001 Oct 1;20(19):5513-20.
  • The absence of SLP65 and Btk blocks B cell development at the preB cell receptor-positive stage.
    Jumaa H, Mitterer M, Reth M, Nielsen PJ.
    Eur J Immunol. 2001 Jul;31(7):2164-9.
  • Oligomeric antigen receptors: a new view on signaling for the selection of lymphocytes.
    Reth M.
    Trends Immunol. 2001 Jul;22(7):356-60.
  • SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates.
    Adachi T, Wienands J, Wakabayashi C, Yakura H, Reth M, Tsubata T.
    J Biol Chem. 2001 Jul 13;276(28):26648-55.
  • Control of cystic fibrosis transmembrane conductance regulator expression by BAP31.
    Lambert G, Becker B, Schreiber R, Boucherot A, Reth M, Kunzelmann K.
    J Biol Chem. 2001 Jun 8;276(23):20340-5.
  • The maintenance and the activation signal of the B-cell antigen receptor.
    Reth M, Wienands J.
    Cold Spring Harb Symp Quant Biol. 1999;64:323-8.
  • An unsolved problem of the clonal selection theory and the model of an oligomeric B-cell antigen receptor.
    Reth M, Wienands J, Schamel WW.
    Immunol Rev. 2000 Aug;176:10-8.
  • Cell cycle arrest and apoptosis induced by Notch1 in B cells.
    Morimura T, Goitsuka R, Zhang Y, Saito I, Reth M, Kitamura D.
    J Biol Chem. 2000 Nov 24;275(47):36523-31.
  • Monomeric and oligomeric complexes of the B cell antigen receptor.
    Schamel WW, Reth M.
    Immunity. 2000 Jul;13(1):5-14.
  • Stability of the B cell antigen receptor complex.
    Schamel WW, Reth M.
    Mol Immunol. 2000 Apr;37(5):253-9.
  • The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction.
    Müller R, Wienands J, Reth M.
    Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8451-4.
  • Comparison of the tamoxifen regulated chimeric Cre recombinases MerCreMer and CreMer.
    Verrou C, Zhang Y, Zürn C, Schamel WW, Reth M.
    Biol Chem. 1999 Dec;380(12):1435-8.
  • Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65.
    Jumaa H, Wollscheid B, Mitterer M, Wienands J, Reth M, Nielsen PJ.
    Immunity. 1999 Nov;11(5):547-54.
  • Interaction of SLP adaptors with the SH2 domain of Tec family kinases.
    Su YW, Zhang Y, Schweikert J, Koretzky GA, Reth M, Wienands J.
    Eur J Immunol. 1999 Nov;29(11):3702-11.
  • Characterization of the B cell-specific adaptor SLP-65 and other protein tyrosine kinase substrates by two-dimensional gel electrophoresis.
    Wollscheid B, Reth M, Wienands J.
    Immunol Lett. 1999 May 3;68(1):95-9.
  • The adaptor protein SLP-65/BLNK controls the calcium response in activated B cells.
    Wollscheid B, Wienands J, Reth M.
    Curr Top Microbiol Immunol. 1999;246:283-8; discussion 288-9.
  • Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk.
    Zhang Y, Wienands J, Zürn C, Reth M.
    EMBO J. 1998 Dec 15;17(24):7304-10.
  • SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation.
    Wienands J, Schweikert J, Wollscheid B, Jumaa H, Nielsen PJ, Reth M.
    J Exp Med. 1998 Aug 17;188(4):791-5.
  • Interaction of the CD5 cytoplasmic domain with the Ca2+/calmodulin-dependent kinase IIdelta.
    Bauch A, Campbell KS, Reth M.
    Eur J Immunol. 1998 Jul;28(7):2167-77.
  • The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation.
    Adachi T, Flaswinkel H, Yakura H, Reth M, Tsubata T.
    J Immunol. 1998 May 15;160(10):4662-5.
  • Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31.
    Annaert WG, Becker B, Kistner U, Reth M, Jahn R.
    J Cell Biol. 1997 Dec 15;139(6):1397-410.
  • Endosomal targeting and the cytoplasmic tail of membrane immunoglobulin.
    Weiser P, Müller R, Braun U, Reth M.
    Science. 1997 Jul 4;277(5322):20-1.
  • Endosomal targeting by the cytoplasmic tail of membrane immunoglobulin.
    Weiser P, Müller R, Braun U, Reth M.
    Science. 1997 Apr 18;276(5311):407-9.
  • Initiation and processing of signals from the B cell antigen receptor.
    Reth M, Wienands J.
    Annu Rev Immunol. 1997;15:453-79.
  • A T cell controlled molecular pathway regulating the IgH locus: CD40-mediated activation of the IgH 3' enhancer.
    Grant PA, Andersson T, Neurath MF, Arulampalam V, Bauch A, Müller R, Reth M, Pettersson S.
    EMBO J. 1996 Dec 2;15(23):6691-700.
  • In vivo and in vitro specificity of protein tyrosine kinases for immunoglobulin G receptor (FcgammaRII) phosphorylation.
    Bewarder N, Weinrich V, Budde P, Hartmann D, Flaswinkel H, Reth M, Frey J.
    Mol Cell Biol. 1996 Sep;16(9):4735-43.
  • Signaling through CD38 augments B cell antigen receptor (BCR) responses and is dependent on BCR expression.
    Lund FE, Yu N, Kim KM, Reth M, Howard MC.
    J Immunol. 1996 Aug 15;157(4):1455-67.
  • Evidence for a preformed transducer complex organized by the B cell antigen receptor.
    Wienands J, Larbolette O, Reth M.
    Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7865-70.
  • Aberrant B cell development and immune response in mice with a compromised BCR complex.
    Torres RM, Flaswinkel H, Reth M, Rajewsky K.
    Science. 1996 Jun 21;272(5269):1804-8.
  • The specificity of association of the IgD molecule with the accessory proteins BAP31/BAP29 lies in the IgD transmembrane sequence.
    Adachi T, Schamel WW, Kim KM, Watanabe T, Becker B, Nielsen PJ, Reth M.
    EMBO J. 1996 Apr 1;15(7):1534-41.
  • Inducible site-directed recombination in mouse embryonic stem cells.
    Zhang Y, Riesterer C, Ayrall AM, Sablitzky F, Littlewood TD, Reth M.
    Nucleic Acids Res. 1996 Feb 15;24(4):543-8.
  • Signaling difference between class IgM and IgD antigen receptors.
    Kim KM, Reth M.
    Ann N Y Acad Sci. 1995 Sep 7;766:81-8.
  • Immunoreceptor tyrosine-based activation motif is required to signal pathways of receptor-mediated growth arrest and apoptosis in murine B lymphoma cells.
    Yao XR, Flaswinkel H, Reth M, Scott DW.
    J Immunol. 1995 Jul 15;155(2):652-61.
  • The B-cell antigen receptor complex and co-receptors.
    Reth M.
    Immunol Today. 1995 Jul;16(7):310-3.
  • The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin kappa.
    Apel TW, Scherer A, Adachi T, Auch D, Ayane M, Reth M.
    Gene. 1995 Apr 24;156(2):191-7.
  • The B cell antigen receptor of class IgD induces a stronger and more prolonged protein tyrosine phosphorylation than that of class IgM.
    Kim KM, Reth M.
    J Exp Med. 1995 Mar 1;181(3):1005-14.
  • The tyrosine activation motif as a target of protein tyrosine kinases and SH2 domains.
    Flaswinkel H, Barner M, Reth M.
    Semin Immunol. 1995 Feb;7(1):21-7.
  • Function of B-cell antigen receptor of different classes.
    Kim KM, Reth M.
    Immunol Lett. 1995 Jan;44(2-3):81-5.
  • Immunodeficiency. Trapping the nude mouse gene.
    Reth M.
    Curr Biol. 1995 Jan 1;5(1):18-20.
  • Two new proteins preferentially associated with membrane immunoglobulin D.
    Kim KM, Adachi T, Nielsen PJ, Terashima M, Lamers MC, Köhler G, Reth M.
    EMBO J. 1994 Aug 15;13(16):3793-800.
  • The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein.
    Terashima M, Kim KM, Adachi T, Nielsen PJ, Reth M, Köhler G, Lamers MC.
    EMBO J. 1994 Aug 15;13(16):3782-92.
  • The internalization of the IgG2a antigen receptor does not require the association with Ig-alpha and Ig-beta but the activation of protein tyrosine kinases does.
    Weiser P, Riesterer C, Reth M.
    Eur J Immunol. 1994 Mar;24(3):665-71.
  • B cell antigen receptors.
    Reth M.
    Curr Opin Immunol. 1994 Feb;6(1):3-8.
  • Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor.
    Flaswinkel H, Reth M.
    EMBO J. 1994 Jan 1;13(1):83-9.
  • Signaling and internalisation function of the B cell antigen receptor complex.
    Flaswinkel H, Weiser P, Kim KM, Reth M.
    Adv Exp Med Biol. 1994;365:1-8.
  • Molecular mimicry of the antigen receptor signalling motif by transmembrane proteins of the Epstein-Barr virus and the bovine leukaemia virus.
    Alber G, Kim KM, Weiser P, Riesterer C, Carsetti R, Reth M.
    Curr Biol. 1993 Jun 1;3(6):333-9.
  • Signalling function of the B-cell antigen receptors.
    Kim KM, Alber G, Weiser P, Reth M.
    Immunol Rev. 1993 Apr;132:125-46. Review.
  • Differential signaling through the Ig-alpha and Ig-beta components of the B cell antigen receptor.
    Kim KM, Alber G, Weiser P, Reth M.
    Eur J Immunol. 1993 Apr;23(4):911-6.
  • The expression of the mouse VpreB/lambda 5 locus in transformed cell lines and tumors of the B lineage differentiation pathway.
    Kudo A, Thalmann P, Sakaguchi N, Davidson WF, Pierce JH, Kearney JF, Reth M, Rolink A, Melchers F.
    Int Immunol. 1992 Aug;4(8):831-40.
  • Crosslinking of the cell surface immunoglobulin (mu-surrogate light chains complex) on pre-B cells induces activation of V gene rearrangements at the immunoglobulin kappa locus.
    Tsubata T, Tsubata R, Reth M.
    Int Immunol. 1992 Jun;4(6):637-41.
  • Glycosyl-phosphatidylinositol linkage as a mechanism for cell-surface expression of immunoglobulin D.
    Wienands J, Reth M.
    Nature. 1992 Mar 19;356(6366):246-8.
  • Molecular cloning of the Ig-alpha subunit of the human B-cell antigen receptor complex.
    Flaswinkel H, Reth M.
    Immunogenetics. 1992;36(4):266-9.
  • Antigen receptors on B lymphocytes.
    Reth M.
    Annu Rev Immunol. 1992;10:97-121.
  • The B cell antigen receptor of class IgD can be expressed on the cell surface in two different forms.
    Wienands J, Reth M.
    Eur J Immunol. 1991 Oct;21(10):2373-8.
  • Regulation of B-cell development by pre-B-cell receptors.
    Reth M.
    Curr Biol. 1991 Jun;1(3):198-9.
  • Signal transduction in B cells.
    Reth M.
    Curr Opin Immunol. 1991 Jun;3(3):340-4.
  • Cell surface expression of the short immunoglobulin mu chain (D mu protein) in murine pre-B cells is differently regulated from that of the intact mu chain.
    Tsubata T, Tsubata R, Reth M.
    Eur J Immunol. 1991 Jun;21(6):1359-63.
  • The B-cell antigen receptor complex.
    Reth M, Hombach J, Wienands J, Campbell KS, Chien N, Justement LB, Cambier JC.
    Immunol Today. 1991 Jun;12(6):196-201.
  • Identification of components of the B cell antigen receptor complex.
    Reth M, Wienands J, Tsubata T, Hombach J.
    Adv Exp Med Biol. 1991;292:207-14.
  • Identification of the genes encoding the IgM-alpha and Ig-beta components of the IgM antigen receptor complex by amino-terminal sequencing.
    Hombach J, Lottspeich F, Reth M.
    Eur J Immunol. 1990 Dec;20(12):2795-9.
  • Exon trap cloning: using PCR to rapidly detect and clone exons from genomic DNA fragments.
    Auch D, Reth M.
    Nucleic Acids Res. 1990 Nov 25;18(22):6743-4.
  • The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface.
    Tsubata T, Reth M.
    J Exp Med. 1990 Sep 1;172(3):973-6.
  • A physical map and analysis of the murine C kappa-RS region show the presence of a conserved element.
    Müller B, Stappert H, Reth M.
    Eur J Immunol. 1990 Jun;20(6):1409-11.
  • Membrane IgM and IgD molecules fail to transduce Ca2+ mobilizing signals when expressed on differentiated B lineage cells.
    Justement LB, Wienands J, Hombach J, Reth M, Cambier JC.
    J Immunol. 1990 May 1;144(9):3272-80.
  • Molecular components of the B-cell antigen receptor complex of the IgM class.
    Hombach J, Tsubata T, Leclercq L, Stappert H, Reth M.
    Nature. 1990 Feb 22;343(6260):760-2.
  • Molecular components of the B cell antigen receptor complex of class IgD differ partly from those of IgM.
    Wienands J, Hombach J, Radbruch A, Riesterer C, Reth M.
    EMBO J. 1990 Feb;9(2):449-55.
  • A novel germ-line JK transcript starting immediately upstream of JK1.
    Leclercq L, Butkeraitis P, Reth M.
    Nucleic Acids Res. 1989 Sep 12;17(17):6809-19.
  • Membrane-bound IgM obstructs B cell development in transgenic mice.
    Müller W, Rüther U, Vieira P, Hombach J, Reth M, Rajewsky K.
    Eur J Immunol. 1989 May;19(5):923-8.
  • Antigen receptor tail clue.
    Reth M.
    Nature. 1989 Mar 30;338(6214):383-4.
  • Ordered activation of the Ig lambda locus in Abelson B cell lines.
    Müller B, Reth M.
    J Exp Med. 1988 Dec 1;168(6):2131-7.
  • A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells.
    Hombach J, Leclercq L, Radbruch A, Rajewsky K, Reth M.
    EMBO J. 1988 Nov;7(11):3451-6.
  • Transfected plasmacytoma cells do not transport the membrane form of IgM to the cell surface.
    Hombach J, Sablitzky F, Rajewsky K, Reth M.
    J Exp Med. 1988 Feb 1;167(2):652-7.
  • Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains.
    Reth M, Petrac E, Wiese P, Lobel L, Alt FW.
    EMBO J. 1987 Nov;6(11):3299-305.
  • VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments.
    Reth MG, Jackson S, Alt FW.
    EMBO J. 1986 Sep;5(9):2131-8.
  • A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production.
    Reth M, Gehrmann P, Petrac E, Wiese P.
    Nature. 1986 Aug 28-Sep 3;322(6082):840-2.
  • Regulation of immunoglobulin variable-region gene assembly.
    Alt FW, Reth MG, Blackwell TK, Yancopoulos GD.
    Mt Sinai J Med. 1986 Mar;53(3):166-9.
  • Regulation of genome rearrangement events during lymphocyte differentiation.
    Alt FW, Blackwell TK, DePinho RA, Reth MG, Yancopoulos GD.
    Immunol Rev. 1986 Feb;89:5-30.
  • Regulated progression of a cultured pre-B-cell line to the B-cell stage.
    Reth MG, Ammirati P, Jackson S, Alt FW.
    Nature. 1985 Sep 26-Oct 2;317(6035):353-5.
  • Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells.
    Reth MG, Alt FW.
    Nature. 1984 Nov 29-Dec 5;312(5993):418-23.
  • Fc-dependent effector functions of idiotype-anti-idiotype immune complexes.
    Rajnavölgyi E, Reth M, Uher F, Miklós K, Gergely J, Rajewsky K.
    Mol Immunol. 1984 Feb;21(2):127-36.
  • Idiotypic determinants used in the analysis of antibody diversification and as regulatory targets.
    Beyreuther K, Bovens J, Brüggemann M, Dildrop R, Kelsoe G, Krawinkel U, Müller C, Nishikawa S, Radbruch A, Reth M, et al.
    Ann N Y Acad Sci. 1983;418:121-9.
  • The immune response against anti-idiotope antibodies. I. Induction of idiotope-bearing antibodies and analysis of the idiotope repertoire.
    Takemori T, Tesch H, Reth M, Rajewsky K.
    Eur J Immunol. 1982 Dec;12(12):1040-6.
  • Somatic variants of murine immunoglobulin lambda light chains.
    Bothwell AL, Paskind M, Reth M, Imanishi-Kari T, Rajewsky K, Baltimore D.
    Nature. 1982 Jul 22;298(5872):380-2.
  • Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.
    Bothwell AL, Paskind M, Reth M, Imanishi-Kari T, Rajewsky K, Baltimore D.
    Cell. 1981 Jun;24(3):625-37.
  • Control of idiotope expression by monoclonal anti-idiotope and idiotope-bearing antibody.
    Kelsoe G, Reth M, Rajewsky K.
    Eur J Immunol. 1981 May;11(5):418-23.
  • Idiotypic regulation by isologous monoclonal anti-idiotope antibodies.
    Reth M, Kelsoe G, Rajewsky K.
    Nature. 1981 Mar 19;290(5803):257-9.
  • Indications for an internal regulation in the immune system.
    Coutinho A, Forni L, Martinez-A C, Bernabé RR, Larsson EL, Reth M, Augustin AA, Cazenave PA.
    Prog Clin Biol Res. 1980;42:279-93.
  • Control idiotope expression by monoclonal anti-idiotope antibodies.
    Kelsoe G, Reth M, Rajewsky K.
    Immunol Rev. 1980;52:75-88.
  • Analysis of the repertoire of anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti-idiotope antibodies.
    Reth M, Imanishi-Kari T, Rajewsky K.
    Eur J Immunol. 1979 Dec;9(12):1004-13.
  • Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response.
    Reth M, Hämmerling GJ, Rajewsky K.
    Eur J Immunol. 1978 Jun;8(6):393-400.
  • Analysis of V gene expression in the immune response by cell fusion.
    Imanshi-Kari T, Reth M, Hämmerling GJ, Rajewsky K.
    Curr Top Microbiol Immunol. 1978;81:20-6.