BIOSS

Centre for Biological Signalling Studies

News

Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters

March 22, 2024 No Comments

2 new DFG research units at the University of Freiburg

The research unit “UcarE – Urothelial Carcinoma Epigenetics” aims to investigate the biological mechanisms that underlie bladder cancer. The unit’s spokesman is Prof Dr Ian

September 22, 2023 No Comments

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Glowing molecules and the memories of plants:

July 28, 2023 No Comments

Events

Daniel B. Werz

Institute of Organic Chemistry, University of Freiburg
Professor

+49 761 203 6031

daniel.werz@chemie.uni-freiburg.de

https://www.werzlab.de/

Curriculum vitae

10 selected publications

Optical Manipulation of Gb3 Enriched Lipid Domains: Impact of Isomerization on Gb3-Shiga Toxin B Interaction. Socrier L, Ahadi S, Bosse M, Montag C, Werz DB*, Steinem C* (2023) Chem Eur J. 28, e2022022766.
The Interaction of Gb₃ Glycosphingolipids with ld/lo Phase Lipids in Lipid Monolayers is a Function of Their Fatty Acids. Socrier L, Bail C, Ackermann E, Beresowski A-K, Ahadi S, Werz DB*, Steinem C* (2022) Langmuir. 38, 5874-5882.
Diversification of 4ʹ-Methylated Nucleosides by Nucleoside Phosphorylases. Kaspar F*, Seeger M, Westarp S, Köllmann C, Lehmann A-P, Pausch P, Kemper S, Neubauer P, Bange G, Schallmey A, Werz DB, Kurreck A (2021) ACS Cat. 11, 10830-10835.
Azide-Functionalized Derivatives of the Virulence-Associated Sugar Pseudaminic Acid: Chiral Pool Synthesis and Labeling of Bacteria. Vibhute AM, Tamai H, Logviniuk D, Jones PG, Fridman M*, Werz DB (2021) Chem Eur J. 27, 10595-10600.
GlycoBODIPYs: Sugars Serving as Natural Stock for Water-soluble Fluorescent Probes of Complex Chiral Morphology. Patalag LJ*, Ahadi S, Lashchuk O, Jones PG, Ebbinghaus S, Werz DB* (2021) Angew Chem. 133, 8848-8853; Angew Chem Int Ed. (2021) 60, 8766-8771.
Differential recognition of lipid domains by two Gb-3 binding lectins. Schubert T, Sych T, Madl J, Xu M, Omidvar R, Patalag LJ, Ries A, Kettelhoit K, Brandel A, Mely Y, Steinem C, Werz DB, Thuenauer R*, Römer W* (2020) Sci Rep. 10, 9752.
Synthesis of Head Group Labeled Gb3 Glycosphingolipids: Distribution in Phase-Separated Giant Unilamellar Vesicles. Sibold J, Kettelhoit K, Vuong L, Liu F, Werz DB*, Steinem C* (2019) Angew Chem. 131, 17969-17977; Angew Chem Int Ed. (2019) 58, 17805-17813.
Shiga toxin binding alters lipid packing and domain structure of Gb3-containing membranes: a solid-state NMR study. Bosse M, Sibold J, Scheidt HA, Patalag LJ, Kettelhoit K, Ries A, Werz DB, Steinem C, Huster D* (2019) Phys Chem Chem Phys. 21, 15630-15638.
Gb3 Glycosphingolipids with Fluorescent Oligoene Fatty Acids: Synthesis and Phase Behavior in Model Membranes. Patalag LJ, Sibold J, Schütte OM, Steinem C*, Werz DB* (2017) ChemBioChem. 18, 2171–2178.
Size, Kinetics and Free Energy of Clusters Formed by Ultraweak Carbohydrate-Carbohydrate Bonds. Witt H, Savic F, Oelkers M, Awan SI, Werz DB, Geil B, Janshoff A* (2016) Biophys J. 110, 1582-1592.