Prof. Dr. Michael Reth

10 Selected publications:

• Antigen receptor function in the context of the nanoscale organization of the B cell membrane.
  Gold MR, Reth MG (2019.
  Annu Rev Immunol. Apr 26;37:97-123
• A symmetric geometry of transmembrane domains inside the B cell antigen receptor complex.
  Gottwick C, He X, Hofmann A, Vesper N, Reth M, Yang J (2019).
  Proc Natl Acad Sci U S A. 116(27):13468-13473.
• Continuous signalling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells.
  He X, Kläsener K, Iype JM, Becker M, Maity PC, Cavallari M, Nielsen PJ, Yang, J, Reth, M (2018).
  EMBO J. 37(11) doi: 10.15252/embj.201797980.
• The BTG2-PRMT2 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex.
  Dolezal E, Infantino S, Drepper F, Börsig T, Singh A, Wossning T, Fiala GJ, Minguet S, Warscheid B, Tarlinton DM, Jumaa H, Medgeysi D, Reth M (2017).
  Nat Immunol 18(8): 911-920.
• B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk.
  Kläsener K, Maity PC, Hobeika E, Yang J, Reth M. (2014).
  Elife 3: e02069.
• Pillars of Immunology article.
  Reth M. (2014).
  J Immunol 192(9):415-416. Reprint of “Antigen receptor tail clue”. Nature (1989).338:383-384.
• Matching cellular dimensions with molecular sizes.
  Reth M.
  Nat Immunol. 2013 Aug;14(8):765-7.
• Oligomeric organization of the B-cell antigen receptor on resting cells.
  Yang J, Reth M (2010).
  Nature 467(7314): 465-469.
• Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia.
  Jumaa H, Bossaller L, Portugal K, Storch B, Lotz M, Flemming A, Schrappe M, Postila V, Riikonen P, Pelkonen J, Niemeyer CM, Reth M (2003).
  Nature 423, 452-456.
• Molecular components of the B-cell antigen receptor complex of the IgM class.
  Hombach J, Tsubata T, Leclercq L, Stappert H, Reth M (1990).
  Nature 343: 760-762.
  Reprinted as Pillars of Immunology in J Immunol (2009) 183: 1505-1507