Prof. Dr. Winfried Römer

10 selected Publications

• Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration.
  Sponsel J, Guo Y, Hamzam L, Lavanant AC, Pérez-Riverón A, Partiot E, Muller Q, Rottura J, Gaudin R, Hauck D, Titz A, Flacher V, Römer W*, Mueller CG*.
  EMBO Rep. 2023 Apr 5;24(4):e55971.
  *corresponding authors
• Neutralizing the Impact of the Virulence Factor LecA from Pseudomonas aeruginosa on Human Cells with New Glycomimetic Inhibitors.
  Zahorska E, Rosato F, Stober K, Kuhaudomlarp S, Meiers J, Hauck D, Reith D, Gillon E, Rox K, Imberty A, Römer W*, Titz A.*
  Angew Chem Int Ed Engl. 2023 Feb 6;62(7):e202215535.
  *corresponding authors
• Septin barriers protect mammalian host cells against Pseudomonas aeruginosa invasion
  Aigal S, Omidvar R, Stober K, Ziegelbauer J, Eierhoff T, Schampera JN, Römer W*, Schwan C.*
  Cell Rep. 2022 Oct 18;41(3):111510.
  corresponding authors*
• Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells.
  Meléndez AV, Velasco Cárdenas RM, Lagies S, Strietz J, Siukstaite L, Thomas OS, Tomisch J, Weber W, Kammerer B, Römer W*, Minguet S.*
  Cell Mol Life Sci. 2022 Sep 12;79(10):513.
  corresponding authors
• The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa.
  Brandel A, Aigal S, Lagies S, Schlimpert M, Meléndez AV, Xu M, Lehmann A, Hummel D, Fisch D, Madl J, Eierhoff T, Kammerer B, Römer W.
  Cell Mol Life Sci. 2021 Apr;78(7):3637-3656.
• Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins.
  Wilhelm I, Levit-Zerdoun E, Jakob J, Villringer S, Frensch M, Übelhart R, Landi A, Müller P, Imberty A, Thuenauer R, Claudinon J, Jumaa H, Reth M, Eibel H, Hobeika E, Römer W (2019).
  Sci Signal. 12(571): eaao7194
• A lipid zipper triggers bacterial invasion.
  Eierhoff T*, Bastian B, Thuenauer R, Madl J, Audfray A, Aigal S, Juillot S, Rydell GE, Müller S, de Bentzmann S, Imberty A, Fleck C*, Römer W* (2014).
  Proc. Natl. Acad. Sci. 111(35): 12895-900 * corresponding author
• Shiga toxins - from cell biology to biomedical applications.
  Johannes L, Römer W (2010).
  Nat Rev Microbiol. 8(2):105-16
• Actin dynamics drive membrane reorganization and scission in clathrin-independent endocytosis.
  Römer W*, Pontani LL, Sorre B, Rentero C, Berland L, Chambon V, Lamaze C, Bassereau P, Sykes C, Gaus K, Johannes L.*
  Cell. 2010 Feb 19;140(4):540-53.
  *corresponding authors
• Shiga toxin induces tubular membrane invaginations for its uptake into cells.
  Römer W, Berland L, Chambon V, Gaus K, Windschiegl B, Tenza D, Aly MR, Fraisier V, Florent J-C, Perrais D, Lamaze C, Raposo G, Steinem C, Sens P, Bassereau P, Johannes L (2007).
  Nature. 450:670-675