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Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters of Excellence BIOSS (Biological Signalling Studies) and CIBSS (Centre for Integrative Biological Signalling Studies). Accompanied by Ms....

2 new DFG research units at the University of Freiburg

The research units are aiming to reveal the potential of enzymatic catalysis and investigate the biological mechanisms that underlie bladder cancer.

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Protein Conducting Nanopores

29.10.2010

Harsman A, Krüger V, Bartsch P, Honigmann A, Schmidt O, Rao S, Meisinger C, Wagner R

J. Phys. Condens. Matter 22, 454102

J. Phys. Condens. Matter online article

Little is known on the molecular nature and mechanisms of the protein translocation channels comprising nanopores. In this paper we highlight recent
developments of the diverse protein translocation systems and focus particularly on the common biophysical properties and functions of the protein conducting nanopores. We also provide a first analysis of the interaction between the genuine protein conducting nanopore Tom40SC as well as a mutant Tom40SC (S54 ? E) containing an additional negative charge with one of its native substrates, CoxIV.