News

Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters of Excellence BIOSS (Biological Signalling Studies) and CIBSS (Centre for Integrative Biological Signalling Studies). Accompanied by Ms....

2 new DFG research units at the University of Freiburg

The research units are aiming to reveal the potential of enzymatic catalysis and investigate the biological mechanisms that underlie bladder cancer.

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Synthetic Immune Signalling

10.02.2012

Schamel WW, Reth M

Curr Opin Biotechnol. 2012;23(5):780-4

Curr Opin Biotechnol. online article

In this BIOSS publication we reviewed old and new technical developments in studying signal transduction mechanisms in immune cells using synthetic biology approaches. These include rebuilding of small functional signaling systems and the design of new molecules acting as signaling switches. In addition we describe how sophisticated engineered immune receptors (chimeric antigen receptors) are being tested in the clinic for gene therapy against tumours.