Synthetic two-way communication between mammalian cells
16.09.2012
Bacchus W, Lang M, El-Baba MD, Weber W, Stelling J, Fussenegger M
Nat Biotechnol. 2012; 30(10):991-6
The design of synthetic biology–inspired control devices enabling entire mammalian cells to receive, process and transfer metabolic information and so communicate with each other via synthetic multichannel networks may provide new insight into the organization of multicellular organisms and future clinical interventions. Here we describe communication networks that orchestrate behavior in individual mammalian cells in response to cell-to-cell metabolic signals.
