Love and death: microglia, NLRP3 and the Alzheimer's brain
12.02.2013
Goldmann T, Tay TL, Prinz M
Cell Res. 2013;23(5):595-6
Microglia were previously attributed to be vital brain guardians for neuronal survival and synaptic pruning during development as well as for the brain's fight against environmental pathogens. A new report, however, sheds new light on these distinct myeloid cells by revealing their deadly nature for mature neurons during neurodegeneration.