BIOSS
Centre for Biological Signalling Studies

Love and death: microglia, NLRP3 and the Alzheimer's brain

12.02.2013

Goldmann T, Tay TL, Prinz M

Cell Res. 2013;23(5):595-6

Cell Res           online article

Microglia were previously attributed to be vital brain guardians for neuronal survival and synaptic pruning during development as well as for the brain's fight against environmental pathogens. A new report, however, sheds new light on these distinct myeloid cells by revealing their deadly nature for mature neurons during neurodegeneration.