News

Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters of Excellence BIOSS (Biological Signalling Studies) and CIBSS (Centre for Integrative Biological Signalling Studies). Accompanied by Ms....

2 new DFG research units at the University of Freiburg

The research units are aiming to reveal the potential of enzymatic catalysis and investigate the biological mechanisms that underlie bladder cancer.

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Synthesis and characterization of a stimulus-responsive l-ornithine-degrading hydrogel

08.11.2012

Geraths C, Eichstädter L, Gübeli RJ, Christen EH, Friedrich C, Weber W.

J Control Release. 2013;165(1):38-43

J Control Release. online article

Hydrogels provide a highly favorable matrix for immobilizing growth factors, enzymes or cells for biomedical applications like tissue engineering, drug delivery or the treatment of metabolic diseases. In this study we describe the synthesis and characterization of a hydrogel able to degrade l-ornithine, a metabolite that is highly elevated in congenital hyperornithinemia. This l-ornithine-degrading hydrogel that can efficiently be eliminated when its functionality is no longer required.