BIOSS
Centre for Biological Signalling Studies

A chemical switch for controlling viral infectivity.

14.09.2014

Hörner M, Kaufmann B, Cotugno G, Wiedtke E, Büning H, Grimm D, Weber W.

Chem Commun (Camb). 2014 Sep 14;50(71):10319-22

Chem Commun (Camb).          online article

Chemically triggered molecular switches for controlling the fate and function of biological systems are fundamental to the emergence of synthetic biology and the development of biomedical applications. We here present the first chemically triggered switch for controlling the infectivity of adeno-associated viral (AAV) vectors.