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Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters of Excellence BIOSS (Biological Signalling Studies) and CIBSS (Centre for Integrative Biological Signalling Studies). Accompanied by Ms....

2 new DFG research units at the University of Freiburg

The research units are aiming to reveal the potential of enzymatic catalysis and investigate the biological mechanisms that underlie bladder cancer.

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Comparison of approaches for parameter identifiability analysis of biological systems

29.01.2014

Raue A, Karlsson J, Saccomani MP, Jirstrand M, Timmer J.

Bioinformatics. 2014;30(10):1440-8

Bioinformatics online article

Modeling of dynamical systems using ordinary differential equations is a popular approach in the field of Systems Biology. We performed a case study using three current approaches for structural identifiability analysis for an application from cell biology. We discuss strength and weaknesses of each of them and illustrate how they can be applied to real world problems.