News

Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters of Excellence BIOSS (Biological Signalling Studies) and CIBSS (Centre for Integrative Biological Signalling Studies). Accompanied by Ms....

2 new DFG research units at the University of Freiburg

The research units are aiming to reveal the potential of enzymatic catalysis and investigate the biological mechanisms that underlie bladder cancer.

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Dpp/BMP signaling in flies: From molecules to biology

09.05.2014

Hamaratoglu F, Affolter M, Pyrowolakis G.

Semin Cell Dev Biol. 2014;32C:128-136

Semin Cell Dev Biol. online article

Signaling by evolutionarily conserved TGFß/BMP ligands controls a vast number of processes during organ and tissue development and homeostasis. Here, we critically review recent developments and findings on BMP signaling in Drosophila, a prime model organism for deciphering TGFß/BMP signaling. We emphasize on transcriptional responses and switches that underlie target gene regulation, on feedback circuitry of the pathway and on the impact of graded BMP signaling in growth, patterning and scaling during organogenesis.