News

Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters of Excellence BIOSS (Biological Signalling Studies) and CIBSS (Centre for Integrative Biological Signalling Studies). Accompanied by Ms....

2 new DFG research units at the University of Freiburg

The research units are aiming to reveal the potential of enzymatic catalysis and investigate the biological mechanisms that underlie bladder cancer.

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Glial epigenetics in neuroinflammation and neurodegeneration

21.03.2014

Staszewski O, Prinz M

Cell Tissue Res. 2014;356(3):609-16

Cell Tissue Res. online article

Epigenetic regulation shapes the differentiation and response to stimuli of all tissues and cells beyond what genetics would dictate. Epigenetic regulation acts through covalent modifications of DNA and histones while leaving the nucleotide code intact. Here we highlight current knowledge about epigenetic changes in glial cells occurring during CNS injury, neuroinflammatory conditions as well as neurodegenerative disease. This review offers an overview about the current understanding of epigenetic regulation in glial cells in CNS disease.