Centrifugo-pneumatic multi-liquid aliquoting -parallel aliquoting and combination of multiple liquids in centrifugal microfluidics
24.06.2015
Schwemmer F, Hutzenlaub T, Buselmeier D, Paust N, von Stetten F, Mark D, Zengerle R, Kosse D
Lab Chip. 2015;15(15):3250-8.
The generation of mixtures with precisely metered volumes is essential for reproducible automation of laboratory workflows. So far no solution exists for assays that require simultaneous aliquoting of multiple, different liquids and the subsequent pairwise combination of aliquots with full fluidic separation before combination. Here, we introduce the centrifugo-pneumatic multi-liquid aliquoting designed for parallel aliquoting and pairwise combination of multiple liquids. All pumping and aliquoting steps are based on a combination of centrifugal forces and pneumatic forces.
