DNA METHYLTRANSFERASE 1 is involved in mCG and mCCG DNA methylation and is essential for sporophyte development in Physcomitrella patens
06.05.2015
Yaari R, Noy-Malka C, Wiedemann G, Auerbach Gershovitz N, Reski R, Katz A, Ohad N.
Plant Mol Biol. 2015;88(4-5):387-400.
DNA methylation has a crucial role in regulating gene expression, signaling pathways and silencing of transposable elements. In plants it occurs at symmetrical CG and CHG contexts and is maintained by two DNA methyltransferase families. While angiosperm genomes encode for several members of MET1 and CMT families, the moss Physcomitrella patens carries a single member of each family. Collectively, our results show functional conservation of MET1 and CMT families in the maintenance of DNA methylation in the epigenetic control of gene expression during land plant evolution..
