BIOSS
Centre for Biological Signalling Studies

Technologies for Single-Cell Isolation

24.07.2015

Gross A, Schoendube J, Zimmermann S, Steeb M, Zengerle R, Koltay P.

Int J Mol Sci. 2015;16(8):16897-919.

Int J Mol Sci.            online article

The handling of single cells is of great importance in applications such as cell line development or single-cell analysis, e.g., for cancer research or for emerging diagnostic methods. This review provides an overview of technologies that are currently used or in development to isolate single cells for subsequent single-cell analysis. These most prominent technologies are described in detail and key performance factors are discussed. Additionally, a worldwide patent search was performed to screen for emerging technologies that might become relevant in the future.