Rapid electron transfer within the III-IV supercomplex in corynebacterium glutamicum
Graf S, Fedotovskaya O, Kao WC, Hunte C, Ädelroth P, Bott M, von Ballmoos C, Brzezinski P
Sci Rep. 2016;6:34098.
The soil bacterium Corynebacterium glutamicum is used for production of glutamate and lysine at megaton scale per year and has superior potential for production of other chemicals. Key component of its aerobic metabolism is a respiratory supercomplex that comprises homologs of mitochondrial respiratory complexes III and IV. The kinetics of electron transfer through both complexes were described, from the b-hemes via the bridging di-heme cytochrome c to heme a and to the heme a3-CuB catalytic site. The data support the functional competence and stability of the isolated supercomplex.
