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Exploring Cutting-Edge Biological Signalling Research in Freiburg

The Lord Mayor of Freiburg, Martin Horn, recently embarked on a visit to the renowned Signalhaus Freiburg, a symbol of research excellence housing the Clusters of Excellence BIOSS (Biological Signalling Studies) and CIBSS (Centre for Integrative Biological Signalling Studies). Accompanied by Ms....

2 new DFG research units at the University of Freiburg

The research units are aiming to reveal the potential of enzymatic catalysis and investigate the biological mechanisms that underlie bladder cancer.

First joint Open Day of CIBSS and BIOSS

In June, the two Freiburg signalling research centres CIBSS and BIOSS gave visitors insights into current research topics.

Events

BIOSS

Stem cell regulation by Arabidopsis WOX genes

19.04.2016

Dolzblasz A, Nardmann J, Clerici E, Causier B, van der Graaff E, Chen J, Davies B, Werr W, Laux T.

Mol Plant. 2016;9(7):1028-39.

Mol Plant online article

In the WUSCHEL-RELATED HOMEOBOX (WOX) gene family, we analyze functional divergence. Members of the WUS clade can substitute for WUS function to different degrees. WUS function requires a canonical WUS-box, whereas the EAR domain is dispensable and the acidic domain seems only to be required for female fertility. Members of the ancient WOX13 and the WOX9 clades cannot support stem cell maintenance. Our results suggest that WUS function is derived and requires yet undiscovered domains.