Spatio-temporal patterning of arginyl-tRNA protein transferase (ATE) contributes to gametophytic development in a moss
02.10.2015
Schuessele C, Hoernstein SN, Mueller SJ, Rodriguez-Franco M, Lorenz T, Lang D, Igloi GL, Reski R
New Phytol. 2016;209(3):1014-27.
N-terminal arginylation is a post-translational modification which plays an integral role in the N-end rule pathway. The reaction is catalyzed by arginyl-tRNA protein transferase (ATE) and its knockout is embryo lethal in mice. Here, the function of ATE in the moss Physcomitrella patens was investigated. Loss of function mutants are severely impaired in gametophyte development, have aberrant plastids and over-accumulate starch. Spatio-temporal pattering of ATE in the gametophyte was investigated via reporter-gene fusion and is linked to plant hormone signaling.
