Low-volume label-free detection of molecule-protein interactions on microarrays by imaging reflectometric interferometry
Burger J, Rath C, Woehrle J, Meyer PA, Ben Ammar N, Kilb N, Brandstetter T, Pröll F, Proll G, Urban G, Roth G.
SLAS Technol. 2017;22(4):437-446
We developed a device for imaging label-free real-time analysis of binding events on surfaces. We describe the device and its functional parts in detail. On several examples we tested the binding events and compared it with state of the art instruments like Biacore.
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