BIOSS
Centre for Biological Signalling Studies

The protein Slr1143 is an active diguanylate cyclase in Synechocystis sp. PCC 6803 and interacts with the photoreceptor Cph2

Angerer V, Schwenk P, Wallner T, Kaever V, Hiltbrunner A, Wilde A

Microbiology. 2017 Jun;163(6):920-930

Microbiology.            online article

Cyclic-di-GMP is a ubiquitous second messenger in bacteria. Several c-di-GMP receptor proteins have been identified to date, and downstream signaling pathways are often mediated through protein-protein interactions. The photoreceptor Cph2 from the cyanobacterium Synechocystis 6803 has been shown to act as a blue-light triggered c-di-GMP producer. In this study, we demonstrate that the protein Slr1143 is a new Cph2-interacting regulatory factor which modulates motility under red light.