The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments
Rampelt H, Sucec I, Bersch B, Horten P, Perschil I, Martinou JC, van der Laan M, Wiedemann N, Schanda P, Pfanner N.
BMC Biol. 2020;18(1):2.
Mitochondria import numerous metabolite carriers that contain an even number of transmembrane segments by a specific pathway. This study reveals an unexpected versatility of the carrier import pathway since substrates with an odd number of transmembrane segments can use the same pathway.